LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 µM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 µM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects[1][2].
Molecular Weight:
245.66
Purity:
99.47
CAS Number:
[2829282-00-8]
Formula:
C10H12ClNO4
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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