NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively[1]. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion[2].
Molecular Weight:
393.45
CAS Number:
[405225-21-0]
Formula:
C24H24FNO3
Target:
GlyT
Application Notes:
MCE Product type: Reference compound
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