VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].
Molecular Weight:
449.57
Purity:
99.71
CAS Number:
[228544-65-8]
Formula:
C25H27N3O3S
Target:
Acyltransferase
Application Notes:
MCE Product type: Reference compound1
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