SD-1008 is a potent JAK inhibitor. SD-1008 inhibits tyrosyl phosphorylation of STAT3, JAK2 and Src. SD-1008 also reduces STAT3-dependent luciferase activity. SD-1008 enhances apoptosis induced by Paclitaxel in ovarian cancer cells via directly blocking the JAK-STAT3 signaling pathway[1].
Molecular Weight:
329.35
Purity:
99.10
CAS Number:
[960201-81-4]
Formula:
C18H19NO5
Target:
Apoptosis,JAK,STAT
Application Notes:
MCE Product type: Reference compound1
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