R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].
Molecular Weight:
459.58
Purity:
99.82
CAS Number:
[93076-89-2]
Formula:
C27H26FN3OS
Target:
5-HT Receptor,PKC
Application Notes:
MCE Product type: Reference compound
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