DKGI-I (hydrochloride), Diacylglycerol kinase inhibitor I (hydrochloride)
R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].
Molecular Weight:
496.04
Purity:
98.88
CAS Number:
[93076-98-3]
Formula:
C27H27ClFN3OS
Target:
5-HT Receptor,PKC
Application Notes:
MCE Product type: Reference compound
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