Milameline (hydrochloride), CAS [[139886-04-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-107650
Supplier Catalog Number:
HY-107650
Alternative Catalog Number:
MCE-HY-107650-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CI 979 (hydrochloride), RU 35926 (hydrochloride)
Milameline (CI 979, RU35926) hydrochloride is a nonselective, partical and orally active muscarinic receptor agonist that improves cognition. Milameline hydrochloride has equal affinity for different subtypes of human muscarinic receptors with IC50 of 1.3 µM for M1-, 1.1 µM for M2-, 1.5 µM for M3-, and 1.9 µM for M4-muscarinic receptors. Milameline hydrochloride has a higher affinity for sites [3H]CMD (IC50 = 20 nM), than [3H]QNB, (IC50 = 3059 nM). Milameline hydrochloride produces both central and peripheral cholinergic effects and reverses the cognitive deficits induced by Scopolamine (HY-N0296). Milameline hydrochloride can be used for the study of Alzheimers Disease[1].
Molecular Weight:
190.67
CAS Number:
[139886-04-7]
Formula:
C8H15ClN2O
Target:
mAChR
Application Notes:
MCE Product type: Reference compound
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