CGP 78608 is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). CGP 78608 has anticonvulsant activities[1][2].
Molecular Weight:
378.12
CAS Number:
[206648-13-7]
Formula:
C11H13BrN3O5P
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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