TCN 213 is a selective, surmountable, glycine-dependentlly GluN1/GluN2A NMDAR antagonist with IC50s of 0.55, 3.5, 40 µM in the presence of 75, 750, 7500 nM glycine, respectively. TCN 213 can be used to monitor, pharmacologically, the switch in NMDAR expression in developing cortical neurones[1][2].
Molecular Weight:
376.54
Purity:
99.16
CAS Number:
[556803-08-8]
Formula:
C18H24N4OS2
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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