JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC50 values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium[1].
Molecular Weight:
449.54
CAS Number:
[148473-36-3]
Formula:
C23H35N3O6
Target:
Neurotensin Receptor
Application Notes:
MCE Product type: Reference compound
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