Paramethasone Acetate is an orally active long-acting glucocorticoid. Paramethasone Acetate directly inhibits testicular aromatase, thereby reducing the synthesis of estradiol. Paramethasone Acetate suppresses the basal and midcycle luteinizing hormone surges in female animals and blocks estrogen synthesis. Paramethasone Acetate also decreases circulating levels of dihydrotestosterone, androstenedione and estradiol in male animals. Paramethasone Acetate inhibits cartilage degeneration and alleviates joint pathological damage in osteoarthritis models. Paramethasone Acetate can be used in research related to osteoarthritis and endocrinology[1][2].
Molecular Weight:
434.50
Purity:
98
CAS Number:
[1597-82-6]
Formula:
C24H31FO6
Target:
Cytochrome P450,Glucocorticoid Receptor
Application Notes:
MCE Product type: Reference compound
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