EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 µM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2[1].
Molecular Weight:
611.60
Purity:
98.03
CAS Number:
[1210945-69-9]
Formula:
C19H20F3N7O7S3
Target:
Complement System
Application Notes:
MCE Product type: Reference compound
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