Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic alpha7 receptor partial agonist, with a Ki of 6 nM for alpha7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM[1].
Molecular Weight:
306.79
Purity:
99.66
CAS Number:
[677305-02-1]
Formula:
C15H19ClN4O
Target:
5-HT Receptor,nAChR
Application Notes:
MCE Product type: Reference compound
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