L-162537 is a competitive human angiotensin II receptor 1 (AT1) and receptor 2 (AT2) antagonist with an IC50=1.7 nM for AT1. L-162537 inhibits Ang II-mediated vasoconstriction, blood pressure elevation and related pathological signaling pathways. L-162537 is promising for research of angiotensin II-related cardiovascular diseases such as hypertension[1].
Molecular Weight:
632.71
CAS Number:
[167027-99-8]
Formula:
C38H32N8O2
Target:
Angiotensin Receptor
Application Notes:
MCE Product type: Reference compound
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