TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCalpha, PKCtheta, and GSK3beta with IC50s of 13, 68, and 3 nM, respectively[1].
Molecular Weight:
526.51
Purity:
99.49
CAS Number:
[1260181-14-3]
Formula:
C27H25F3N4O4
Target:
GSK-3,JAK,PKC
Application Notes:
MCE Product type: Reference compound
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