PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM[1]. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate[2].
Molecular Weight:
439.94
Purity:
99.89
CAS Number:
[1469284-78-3]
Formula:
C22H26ClN7O
Target:
Acyltransferase
Application Notes:
MCE Product type: Reference compound
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