Deltazinone 1, a pyrazolopyridazinone, is a highly selective PDEdelta inhibitor with a KD of 8 nM. Deltazinone 1 inhibits the PDEdelta-Ras interaction. Deltazinone 1 shows a dose-dependent inhibitory response on proliferation in oncogenic KRas-dependent cell lines[1][2].
Molecular Weight:
457.57
CAS Number:
[894554-89-3]
Formula:
C27H31N5O2
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound1
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