(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 µM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 µM[1].
Molecular Weight:
329.17
CAS Number:
[884338-18-5]
Formula:
C19H15FeNO
Target:
VEGFR
Application Notes:
MCE Product type: Reference compound
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