ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 µM and 52.99 µM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral[1].
Molecular Weight:
362.42
Purity:
99.44
CAS Number:
[332382-54-4]
Formula:
C22H22N2O3
Target:
Dengue Virus,Flavivirus,TRP Channel
Application Notes:
MCE Product type: Reference compound
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