PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 µM[1], and a relative binding affinity (Kd) of 150 µM in Ln229 cells[3].
Molecular Weight:
274.79
Purity:
99.27
CAS Number:
[1050480-30-2]
Formula:
C16H19ClN2
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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