AMG-548 (hydrochloride), CAS [[2437438-16-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-108642A
Supplier Catalog Number:
HY-108642A
Alternative Catalog Number:
MCE-HY-108642A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
AMG-548 hydrochloride, an orally active and selective p38alpha inhibitor (Ki=0.5 nM), shows slightly selective over p38beta (Ki=36 nM) and >1000 fold selective against p38gamma and p38delta. AMG-548 hydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFalpha (IC50=3 nM)[1]. AMG-548 hydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms delta and epsilon[2].
Molecular Weight:
498.02
CAS Number:
[2437438-16-7]
Formula:
C29H28ClN5O
Target:
Casein Kinase,p38 MAPK
Application Notes:
MCE Product type: Reference compound
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