AL 8697 is a specific and orally active p38alpha MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38alpha compared to p38beta (IC50=82 nM), and 300-fold selectivity for p38alpha over a panel of 91 kinases. Anti-inflammatory activity[1].
Molecular Weight:
402.41
Purity:
99.83
CAS Number:
[1057394-06-5]
Formula:
C21H21F3N4O
Target:
Autophagy,p38 MAPK
Application Notes:
MCE Product type: Reference compound
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