BI-3802, a chemical probe, is a highly potent BCL6 degrader and inhibits the Bric-a-brac (BTB) domain of BCL6 with an IC50 of 3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity[1][2].
Molecular Weight:
484.98
Purity:
99.43
CAS Number:
[2166387-65-9]
Formula:
C24H29ClN6O3
Target:
Bcl-2 Family,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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