VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1].
Molecular Weight:
387.80
Purity:
99.55
CAS Number:
[1809085-30-0]
Formula:
C18H15ClFN5O2
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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