Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit, VEGFR-2 and PDGFRbeta with IC50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively[1]. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis[2].
Molecular Weight:
410.48
Purity:
98.13
CAS Number:
[1044040-56-3]
Formula:
C23H27FN4O2
Target:
Apoptosis,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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