Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRalpha, VEGFR2, FGFR1, and Src, respectively[1].
Molecular Weight:
569.02
Purity:
99.76
CAS Number:
[1114544-31-8]
Formula:
C29H28ClF3N6O
Target:
Autophagy,Bcr-Abl,FGFR,PDGFR,Src,VEGFR
Application Notes:
MCE Product type: Reference compound
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