Sodium thiosulfate is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3beta and beta-catenin proteins, reduces IL-1beta, COX-2, and Iba-1, and inhibits NFkappaB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease[1][2][3][4][5][6][7][8][9].
