Canakinumab (ACZ885) is a recombinant human anti-IL-1beta monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1beta, respectively. The mode of action of canakinumab is based on the neutralization of IL-1beta signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].
Molecular Weight:
(145.5 kDa)
Purity:
99.64
CAS Number:
[914613-48-2]
Target:
Interleukin Related
Application Notes:
MCE Product type: Inhibitory Antibodies
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