Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-beta/smad2 signaling pathway[1][2][3].
Molecular Weight:
111.14
Purity:
99.86
CAS Number:
[62637-93-8]
Formula:
C3H13NO3
Target:
Endogenous Metabolite,NOD-like Receptor (NLR),Reactive Oxygen Species (ROS),TGF-beta/Smad
Application Notes:
Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted