LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 µM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 (IC50=5 µM) and SHP2 (IC50=2.5 µM). LYP-IN-1 exhibits highly efficacious cellular activity in T- and mast cells. LYP-IN-1 can be used for the study of autoimmune disorders[1]. LYP-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
501.91
Purity:
99.82
CAS Number:
[1404436-51-6]
Formula:
C28H20ClNO6
Target:
Phosphatase,SHP1,SHP2
Application Notes:
MCE Product type: Reference compound1
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