Pyrazoloacridine (NSC 366140), an intercalating agent with anti-cancer activity, inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine (NSC 366140) exhibits an IC50 of 1.25 µM in K562 myeloid leukemia cells for 24 h treatment[1][2].
Molecular Weight:
367.40
Purity:
98.05
CAS Number:
[99009-20-8]
Formula:
C19H21N5O3
Target:
Apoptosis,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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