Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 (SV2) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABAAR, with high potency against alpha1 and alpha5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models[1][2].
Molecular Weight:
432.80
Purity:
99.65
CAS Number:
[1294000-61-5]
Formula:
C14H14ClF5N4O2S
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
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