Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis[1][2][3].
Molecular Weight:
470.52
Purity:
98.11
CAS Number:
[1353552-97-2]
Formula:
C26H26N6O3
Target:
BMX Kinase,Btk,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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