Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Abeta reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimers Disease treatment[1].
Molecular Weight:
367.40
Purity:
99.77
CAS Number:
[1200493-78-2]
Formula:
C18H14FN5OS
Target:
Beta-secretase
Application Notes:
Reference compound
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