Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor (Ki=200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats[1][2].
Molecular Weight:
368.51
Purity:
98
CAS Number:
[648927-86-0]
Formula:
C8H20N2O6S4
Target:
Aminopeptidase
Application Notes:
MCE Product type: Reference compound1
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