Lazertinib (mesylate) (YH25448 (mesylate), GNS-1480 (mesylate)) is an orally active EGFR inhibitor that can penetrate the blood-brain barrier. Lazertinib (mesylate) inhibits p-EGFR, p-AKT and p-ERK signaling pathways, leading to apoptosis. Lazertinib (mesylate) has anti-tumor activity in the mouse H1975-luc BM xenograft model. Lazertinib (mesylate) can be used in the study of non-small cell lung cancer[1].
Molecular Weight:
650.75
Purity:
99.85
CAS Number:
[2247995-37-3]
Formula:
C31H38N8O6S
Target:
Akt,EGFR,ERK
Application Notes:
MCE Product type: Reference compound1
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