Upacicalcet (sodium), CAS [[2052969-18-1]]

Product Overview

• Article Name: Upacicalcet (sodium), CAS [[2052969-18-1]]
• Biozol Catalog Number: MCE-HY-109106A
• Supplier Catalog Number: HY-109106A
• Alternative Catalog Number: MCE-HY-109106A-100MG,MCE-HY-109106A-10MG,MCE-HY-109106A-50MG,MCE-HY-109106A-10MMX1ML,MCE-HY-109106A-5MG,MCE-HY-109106A-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: SK-1403, AJT240, PLS240

Product Description

Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT[1][2].

Product Properties

• Molecular Weight: 373.75
• Purity: 99.91
• CAS Number: [2052969-18-1]
• Formula: C11H13ClN3NaO6S
• Target: CaSR

Application Notes

• Application Notes: MCE Product type: Reference compound