(Rac)-Upacicalcet, CAS [[2649575-19-7]]

Product Overview

• Article Name: (Rac)-Upacicalcet, CAS [[2649575-19-7]]
• Biozol Catalog Number: MCE-HY-109106B
• Supplier Catalog Number: HY-109106B
• Alternative Catalog Number: MCE-HY-109106B-10MG,MCE-HY-109106B-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (Rac)-SK-1403 (free acid), (Rac)-AJT240 (free acid), (Rac)-PLS240 (free acid)

Product Description

(Rac)-Upacicalcet is the racemate of Upacicalcet (HY-109106). Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT[1][2].

Product Properties

• Molecular Weight: 351.76
• Purity: 95
• CAS Number: [2649575-19-7]
• Formula: C11H14ClN3O6S
• Target: CaSR

Application Notes

• Application Notes: MCE Product type: Reference compound