Lorpucitinib (JNJ-64251330) is an orally active pan-JAK inhibitor. Lorpucitinib inhibits all four human JAKs, with greatest potency toward JAK1/JAK3 and JAK1/TYK2 heterodimers, and reduces STAT-3 phosphorylation downstream of JAK signaling. Lorpucitinib can be used for the research of gastrointestinal inflammatory diseases[1].
Molecular Weight:
408.50
Purity:
99.95
CAS Number:
[2230282-02-5]
Formula:
C22H28N6O2
Target:
JAK,STAT
Application Notes:
MCE Product type: Reference compound
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