Murizatoclax (AMG 397) is a potent, selective and orally active inhibitor of myeloid leukemia 1 (MCL-1) inhibitor, with a Ki of 15 pM. Murizatoclax competitive binds to the BH3-binding groove of MCL1 with pro-apoptotic BCL-2 family members. Murizatoclax can be used for the research of cancer[1][2].
Molecular Weight:
765.44
Purity:
98.84
CAS Number:
[2245848-05-7]
Formula:
C42H57ClN4O5S
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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