C-1311 shows to inhibit the catalytic activity of DNA topoisomerase II in vitro and in tumour cells. C-1311 prolongs G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe[1].
Molecular Weight:
350.41
CAS Number:
[138154-39-9]
Formula:
C20H22N4O2
Target:
Mitosis,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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