Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). The antibody portion is Gemtuzumab (HY-P99971), and the drug-linker conjugate for ADC is N-Ac-gamma-Calicheamicin-AcBut-NHS ester (HY-103688). Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML)[1][2].
Molecular Weight:
151000 (average)
Purity:
98.00
CAS Number:
[220578-59-6]
Target:
Antibody-Drug Conjugates (ADCs),Apoptosis
Application Notes:
MCE Product type: ADC Related
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