4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9[1].
Molecular Weight:
405.53
Purity:
96.89
CAS Number:
[865536-65-8]
Formula:
C26H31NO3
Target:
Apoptosis,Drug Metabolite,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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