Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2[1][2]. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity[3][4].
Molecular Weight:
317.38
Purity:
99
CAS Number:
[803712-67-6]
Formula:
C20H19N3O
Target:
Autophagy,Bcl-2 Family,Parasite
Application Notes:
MCE Product type: Reference compound1
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