Alisertib (sodium), CAS [[1028486-06-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10971A
Supplier Catalog Number:
HY-10971A
Alternative Catalog Number:
MCE-HY-10971A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
MLN 8237 (sodium)
Alisertib (MLN 8237) sodium is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib sodium induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity[1][2][3].
Molecular Weight:
540.91
CAS Number:
[1028486-06-7]
Formula:
C27H19ClFN4NaO4
Target:
Apoptosis,Aurora Kinase,Autophagy
Application Notes:
MCE Product type: Reference compound
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