Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib (HY-10977). Tivozanib hydrochloride hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrochloride hydrate exhibits antitumor efficacy[1].
Molecular Weight:
509.34
Purity:
99.83
CAS Number:
[682745-41-1]
Formula:
C22H22Cl2N4O6
Target:
VEGFR
Application Notes:
MCE Product type: Reference compound
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