Amonafide (dihydrochloride), CAS [[150091-68-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-10982A
Supplier Catalog Number:
HY-10982A
Alternative Catalog Number:
MCE-HY-10982A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
AS1413 (dihydrochloride)
Amonafide dihydrochloride (AS1413 dihydrochloride) is a topoisomerase II (Topo II) inhibitor and DNA intercalator with activity in inducing apoptotic signaling. Amonafide dihydrochloride can inhibit the binding of Topo II to DNA, thereby preventing the synthesis of DNA and RNA. Amonafide dihydrochloride maintains cytotoxic activity in the presence of P-glycoprotein-mediated multidrug resistance (MDR)[1].
Molecular Weight:
356.25
CAS Number:
[150091-68-2]
Formula:
C16H19Cl2N3O2
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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