VO-OHPic is a reversible, noncompetitive and selective PTEN inhibitor with an IC50 of 46 nM. VO-OHPic attenuates apoptosis, adverse cardiac remodeling, and pro-inflammatory M1 macrophages in doxorubicin-induced cardiomyopathy. VO-OHPic inhibits autophagy[1][2][3].
Molecular Weight:
361.16
CAS Number:
[675848-25-6]
Formula:
C12H10N2O8V
Target:
Apoptosis,Autophagy,PTEN
Application Notes:
MCE Product type: Reference compound
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