Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids[1][2].
Molecular Weight:
378.39
Purity:
99.85
CAS Number:
[1110781-88-8]
Formula:
C20H21F3N2O2
Target:
Trace Amine-associated Receptor (TAAR)
Application Notes:
MCE Product type: Reference compound
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