CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 µM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9[1].
Molecular Weight:
324.76
Purity:
98.51
CAS Number:
[310460-39-0]
Formula:
C18H13ClN2O2
Target:
DOCK
Application Notes:
MCE Product type: Reference compound1
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